Publications - MIT Yang Tan Collective

Targeting thalamic circuits rescues motor and mood deficits in PD mice

Nature July 1, 2022 Zhang Y, Roy DS, Zhu Y, Chen Y, Aida T, Hou Y, Shen C, Lea NE, Schroeder ME, Skaggs KM, Sullivan HA, Fischer KB, Callaway EM, Wickersham IR, Dai J, Li XM, Lu Z, Feng G

Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex

Cell May 27, 2022 Kato K, Zhou W, Okazaki S, Isayama Y, Nishizawa T, Gootenberg JS, Abudayyeh OO, Nishimasu H

Anterior thalamic circuits crucial for working memory

Proc Natl Acad Sci U S A May 10, 2022 Roy DS, Zhang Y, Aida T, Shen C, Skaggs KM, Hou Y, Fleishman M, Mosto O, Weninger A, Feng G

Tuning the Sensitivity of Genetically Encoded Fluorescent Potassium Indicators through Structure-Guided and Genome Mining StrategiesClick to copy article link

ACS Sensors April 15, 2022 Torres Cabán CC, Yang M, Lai C, Yang L, Subach FV, Smith BO, Piatkevich KD, Boyden ES

Multi-animal pose estimation, identification and tracking with DeepLabCut

Nat Methods April 1, 2022 Lauer J, Zhou M, Ye S, Menegas W, Schneider S, Nath T, Rahman MM, Di Santo V, Soberanes D, Feng G, Murthy VN, Lauder G, Dulac C, Mathis MW, Mathis A

The preference for sugar over sweetener depends on a gut sensor cell

Nature Neuroscience February 1, 2022 Buchanan KL, Rupprecht LE, Kaelberer MM, Sahasrabudhe A, Klein ME, Villalobos JA, Liu WW, Yang A, Gelman J, Park S, Anikeeva P, Bohórquez DV

Thalamic subnetworks as units of function

Nature Neuroscience January 31, 2022 Roy DS, Zhang Y, Halassa MM, Feng G

The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases

Science September 9, 2021 Altae-Tran H, Kannan S, Demircioglu FE, Oshiro R, Nety SP, McKay LJ, Dlakić M, Inskeep WP, Makarova KS, Macrae RK, Koonin EV, Zhang F

Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery

Science August 20, 2021 Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F

Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models

Nature August 18, 2021 Roy DS, Zhang Y, Aida T, Choi S, Chen Q, Hou Y, Lea NE, Skaggs KM, Quay JC, Liew M, Maisano H, Le V, Jones C, Xu J, Kong D, Sullivan HA, Saunders A, McCarroll SA, Wickersham IR, Feng G

Enhanced rationality in autism spectrum disorder

Trends in Cognitive Sciences July 2, 2021 Rozenkrantz L, D'Mello A, Gabrieli JDE

Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair

Cell June 10, 2021 Wilde JJ, Aida T, Del Rosario RCH, Kaiser T, Qi P, Wienisch M, Zhang Q, Colvin S, Feng G